Optimizing Radiation Dose for Early-Stage Extranodal Nasal-Type NK/T-Cell Lymphoma

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Unfavorable prognosis of elderly patients with early-stage extranodal nasal-type NK/T-cell lymphoma.

BACKGROUND Extranodal nasal-type NK (natural killer)/T-cell lymphoma in elderly patients is rare, and its prognosis is unclear. This study aims to investigate the clinical characteristics and prognosis of this lymphoma. PATIENTS AND METHODS We analyzed 24 patients (age, >60 years old) with early-stage extranodal nasal-type NK/T-cell lymphoma. Among these patients, 23 received radiotherapy alo...

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BACKGROUND AND OBJECTIVE The objective of the study was to evaluate the efficiency of chemotherapy (CT) combined with high-dose extended-field radiotherapy (RT) in stage I extranodal nasal-type natural killer/T-cell lymphoma (NKTCL). PATIENTS AND METHODS Between January 2001 and November 2010, 103 stage I extranodal nasal-type NKTCL patients were retrospectively analyzed. Of these patients, 7...

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Lymphocyte/Monocyte Ratio is a Novel Predictor for Early Stage Extranodal Natural Killer/T-cell Lymphoma, Nasal Type

Objective: Great heterogeneity exists in clinical behavior and survival outcome in patients with stage IE/IIE extranodal natural killer/T-cell lymphoma, nasal type (ENKTL). In this study, we proposed lymphocyte/monocyte ratio (LMR) as a new prognostic factor for these early stage ENKTL. Methods: We retrospectively examined the LMR as a prognostic variable in a cohort of 379 patients with newly ...

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Risk-adapted therapy for early-stage extranodal nasal-type NK/T-cell lymphoma: analysis from a multicenter study.

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Extranodal NK/T cell lymphoma (ENKTL), nasal type is a rare, aggressive disease affecting the midfacial and nasopalatal region in the head. The pathogenesis of the disease is unknown, but the disease has been linked to Epstein Barr virus (EBV) infection. Early diagnosis of the disease is the best way to increase the prognosis and quality of life in the patients. However, it is still a challenge...

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ژورنال

عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics

سال: 2016

ISSN: 0360-3016

DOI: 10.1016/j.ijrobp.2016.06.419